Protein Details: Gap junction alpha-2 protein

Protein ID

ICDB_Pro_0363

Protein Name

Gap junction alpha-2 protein

Gene Name

gja2

Organism

Xenopus laevis (African clawed frog)

Length

334 amino acids

AlphaFoldDB

AF-P16864-F1-model_v4.pdb

Function

Sequence

MAGWELLKLLLDDVQEHSTLIGKVWLTVLFIFRIFILSVAGESVWTDEQSDFICNTQQPGCTNVCYDQAFPISHVRYWVLQFLFVSTPTLIYLGHMVYLSKKEEKERQKENESRILVANEAQTEVHSSATKKIRIQGPLMCTYTTSVVFKSIFEAGFLLGQWYIYGFVMSPIFVCERIPCKHKVECFVSRPMEKTIFIIFMLVVSLISLLLNLMELIHLSFKCFQHGIKEGATCSPTGIPFNGAGNRMPPQEYTNPPSSNQDIDLPSYNKMSGGHNWSRIQMEQQVNGLVKPKCQCDCWSQSAISVVVSGAPGIISNMDAVKSNHQTSSKQQYV

PDB Structures

Ligand Binding

1. DICL_CP

2. DICL_Pep

Binding Site

Disease

Location

Resides primarily in the ovary; oocytes and early embryos

DOI ID

10.1083/jcb.110.3.597; 10.1126/science.2466337

RefSeq

XP_018103585.1; XP_018103586.1